BACH and BACH-MIX

BACH: Bayesian 3D constructor for Hi-C data

BACH users' manual
BACH source code
BACH sample input data
BACH sample output data

BACH-MIX: an extended BACH algorithm to characterize structural variations of chromatin folding

BACH-MIX users' manual
BACH-MIX source code
BACH-MIX sample input data
BACH-MIX sample output data

Movies of the BACH predicted 3D chromosomal structure of chromosome 2 in the mouse ES cells in the HindIII sample

The 3D chromosomal structure spins around the z-axis
The 3D chromosomal structure spins around the x-axis

Comments, suggestions, questions are welcomed, and should be directed to Ming Hu. Email: minghu@fas.harvard.edu.

If you use BACH adn BACH-MIX, please cite our paper:

Hu M, Deng K, Qin Z, Dixon J, Selvaraj S, Fang J, Ren B, Liu JS. (2013) Bayesian Inference of Spatial Organizations of Chromosomes. PLoS Computational Biology 9(1): e1002893.

Last modified on 02/01/2013