Brad Johnson, MD PhD (2004-2008)
With Brad Johnson, I've completed projects that investigated protein expression changes during senescence and explored the in vivo role of g-quadruplexes in yeast.
With Brad Johnson, I've completed projects that investigated protein expression changes during senescence and explored the in vivo role of g-quadruplexes in yeast.
I began working with Li-San Wang during the g-quadruplex project. During the summer of 2007, we applied machine learning algorithms to microarrays and studed distance correction functions in phylogenetic trees. This work was a part of the Undergraduate Interdisciplinary Research Summer Internship Program, a 8-week program run by the Penn Genomics Institute. We are currently working with Dr. Johnson to further explore the role of quadruplexes. We are especially interested in the conservation of their functions.
Starting in the summer of 2007, I worked in Christopher Murray's lab developing tools to extend Materials Studio to help us make and mold particles of various shapes. I also wrote a Perl/C++ program that computes X-ray diffraction patterns.
During my first year of graduate school, I had the opporunity to work on projects in stellar laboratories of Manolis Kellis, Angela DePace with Martha Bulyk, Alan Saghatelian, Gavin MacBeath, and Tim Mitchison with Hanno and Judith Steen, before joining the lab of Vamsi Mootha.
For my PhD thesis, I've joined the lab of Vamsi Mootha where I use next generation sequencing to discover causes of mitochondrial diseases.