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Dr. Anita Goel, MD, PhD

goel@physics.harvard.edu

Research Interests

Positions &  Affiliations

Publications

Invited Talks

Selected Press & Honors


 

drgoel


M.D., Harvard-MIT, Division of Health Sciences and Technology     hst
Ph.D., M.A., Harvard University, Physics       h

B.S., Stanford University, Physics    st

 

 

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Research Interests 

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Fundamental Science
Elucidate the physics of living systems, especially at the nanoscale:
  • Develop novel conceptual frameworks and theoretical models to describe molecular motors: the dynamics, energy transduction, and coupling to their environment
  • Develop nanoscale techniques to precision control nanomachines and harness them for nanomanufacturing
  • Quantum Mechanics:  Foundations and its role in life
  • Foundational Questions in Theoretical Physics

Applied Science via the Nanobiosym Research Institute
Develop next-generation nano-enabled platforms for:
  • Pathogen detection, including biosensors and biosurveillance systems
  • Nanoscale diagnostic kits for molecular biology and clinical medicine
  • Rapid detection and response capabilities to public health outbreaks like SARS and avian flu
  • Nanobio computing architectures, including quantum information processing by nanomachines
  • Energy harvesting, including ultra-efficient nanobio power generators

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Positions & Affiliations 

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Nanobiosym Research Institute
Chairman & Scientific Director
Nanobiosym Labs was founded to discover scientific insights and technologies that emerge from the holistic integration of physics, nanotechnology and biomedicine, with a particular focus on using physics to more deeply understand living systems and biomedical processes.

Nanobiosym Diagnostics
President & CEO
Nanobiosym Diagnostics is  developing next-generation diagnostic capabilities, including the Gene-RADAR platform for point-of-care diagnostics

The Board of Overseers of the Museum of Science, Boston
June, 2008 - Present

Indus Entrepreneurs TiE
Charter Member

BEYOND: Center for Fundamental Concepts in Science
Adjunct Professor
BEYOND is a pioneering international center led by physicist and cosmologist Paul Davies based at Arizona State University specifically dedicated to pushing the boundaries of research 'beyond' by confronting the big questions of existence raised by stunning new scientific advances and facilitating new research initiatives that transcend traditional subject categories

Harvard University, Department of Physics
Associate (2002- Present)

Santa Fe Institute
Fellow-at-Large
A multi-disciplinary institute and think tank dedicated to understanding complexity, especially as it arises in natural, artificial and social systems
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Selected Publications

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  1. A. Goel and V. Vogel, "Harnessing biological motors to engineer systems for nanoscale transport and assembly," Nature Nanotechnology 3, 465-475 (2008).
  2. A. Goel, "Molecular Evolution: a role for quantum mechanics in the dynamics of molecular machines that reac DNA" in Quantum Aspects Of Life, ed. by Derek Abbott, Paul Davies and Arun K. Pati. Singapore: World Scientific, 2008.
  3. I. Andricioaei, A. Goel, D.R. Herschbach and M. Karplus, “Dependence of DNA polymerase replication rate on external forces: A model based on molcular dynamics simulations,” Biophysics J., 87, 2004.
  4. A. Goel, R.D. Astumian and D.R. Herschbach,“Tuning and Swtiching a DNA Polymerase Motor with  Mechanical Tension,” in Proc. of the National Academy of Science, USA, 100, 17, pp. 9699-9704, August 2003.
  5. A. Goel and D.R. Herschbach, “Controlling the Speed and Direction of Molecular Motors that Replicate DNA,” in Fluctuations and Noise in Biological, Biophysical and Biomedical Systems, Proc. of SPIE, 5110, pp. 63-68, 2003.
  6. A. Goel, T. Ellenberger, M.D. Frank-Kamenetskii and D. Herschbach, “Unifying Themes in DNA Replication: Reconciling Single Molecule Kinetic Studies with Structrual Data on DNA Polymerases,” J. Biolmolecular Structure and Dynamics, (Cover), 19, 4, 2002.
  7. A. Goel, M.D. Frank-Kamenetskii, T. Ellenberger and D. Herschbach, “Tuning DNA ‘Strings’: Modulating the Rate of DNA Replication with Mechanical Tension,” Proc. of the National Academy of Science, USA, 98, 15, pp. 8485-8489.
  8. A. Goel, “The Physics of Life” paper presented at the Science and Ultimate Reality Symposium, Young Researcher’s Competition in Honor of John Archibald Wheeler, Princeton, New Jersey, March, 2002. See Also Physics Today -May, 2002.

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Invited Talks & Keynotes

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2009

Invited Address, Annual Leonardo DaVinci Symposium on Engineering and Physical Biology, Harvard University, April 23, 2009


Guest Faculty Lecture, Harvard/MIT Health Science and Technology HST 921, ‘Information Technology in the Healthcare System of the Future,’ Harvard Medical School, April 16, 2009


Guest Faculty Lecture, Harvard Kennedy School, Science, Technology and Innovation Policy Program, ‘Biomedical Technology,’ April 16, 2009 (Invited by Prof. C. Juma)
This  Innovation for Economic Development program at Harvard Kennedy School provides high-level leaders from government, academia, industry, and civil society with a unique opportunity to explore how to harness the power of emerging technologies to promote prosperity. The program focuses on how to design and implement innovation policies for economic development.


Invited Speaker, Harvard Kennedy School 15th Annual International Development Conference, Panel of Technological Innovations in Development: Trends in Using Technology to Improve Service Delivery, April 4, 2009   


Keynote Lunch  Address, “Nanotechnology and Regulation Issues” Food and Drug Law Institute, 2nd Annual Conference on Nanotechnology Law, Regulation and Policy, Washington DC, February 19, 2009


Invited Speaker, Gordon Research Conference on Chemical and Biological Terrorism Defense, Hotel Galvez, Galveston, TX, January 20, 2009


Invited Speaker: “Quantum aspects of biology: a role for quantum mechanics in bio-machines” at
Workshop on Quantum Technologies in Biological Systems, National University of Singapore Centre for Quantum Technologies, Singapore, January 15, 2009


Keynote Address, “Harnessing nanotechnology to accelerate the growth engine of India” at Bio-Partnering Gujarat, Gujarat Global Investor Summit 2009, Science City, Ahmedabad, January 13, 2009

2008

IGERT Nanomedicine Distinguished Lecture, “Harnessing Biological Motors to Engineer Systems for Nanoscale Transport and Assembly,” Northeastern University, December 5, 2008


Invited Speaker: DARPA Conference, Quantum Effects in Biological Environments, Arlington, VA,October 14, 2008



Invited Speaker, MIT Sloan School of Management, BioInnovations 2008, Pathways to Innovation Panel on "Social Entrepreneurship: An In-Depth Look at For-Profit vs. Non-Profit Models, " MIT, April 18, 2008

Invited Speaker, Johnson & Johnson Press Breakfast, American Association for the Advancement of Science Annual Conference, Boston, MA, February 16, 2008

Conference Keynote, Round Table on Entrepreneurial Leadership, Leadership and Innovation Conference, New York, February, 2008


Invited Speaker, National Institute of Standards and Technology (NIST), Nanotechnology Based Bio-detection Sensors,
Germantown, MD. January 15, 2008


2007

Session Co-Chairman (with Roger Kornberg, Nobel Laureate, Chemistry, 2006), All India Student Conference: Science and the Spiritual Quest – East vs. West. Tirupati, India, December 23, 2007

Keynote Speaker and Inaugural Addresss, VYASA International Conference on Frontiers in Yoga: Research and Applications:  Emerging Trends in Nanotechnology and its Relevance in Yoga Research, Bangalore, India, December 20-21,2007
Invited Address and Panel Chair, National Symposium for the Advancement of Women in Science, Above and Beyond the Glass Ceiling, Harvard University, Cambridge, MA, April 13 -15, 2007

Invited Colloquium Speaker: Department of Physics Colloquium, University of Waterloo Waterloo, Canada, March 1, 2007. Invited by Prof. Robert Mann

Invited Speaker, Harvard Business School Conference on India: Entrepreneurship in Emerging Markets. Cambridge, MA. January 26, 2007

2006
Annual Keynote Address, Banyan Ball, Ybor City Museum, Indo-US Chamber of Commerce Annual Black Tie Ball. Tampa Bay, FL, December 9, 2006

Award Acceptance Speech, Global Indus Technovators Award, Conference on Advances in Nanotechnology, MIT, Cambridge, MA, December 4, 2006

Invited Speaker, Nano-enabled Biodefense Applications, Defense Threat Reduction Agency (DTRA), Washington D.C., September 22, 2006

Invited Speaker: US Frontiers of Engineering Symposium, Top 100 Engineers invited to participate in National Academy of Engineering, Deerfield, MI, September 21-23, 2006

Invited Keynote Speaker,  IDEA, Ascona, Switzerland, September 18-22, 2006. Invited by Viola Vogel.

Invited Speaker: “Nano-Enabled Platform for Pathogen Detection,” Micro/Nano Technologies for National Security Applications - ­Biological/Chemical Defense Session, NSTI Nanotechnology Conference, Boston, MA, May 8, 2006

Invited Speaker: “Nano-­Enabled Devices and Systems for Defense Applications,” DARPA-­MTO Workshop, Colorado Springs, CO, April 12, 2006

Invited Speaker: “Beyond Small” Panel, WEST Technology and Innovation Showcase, 2006, Boston, MA, April 6, 2006

Invited Speaker: Plenary Session, “World of Nano: The Exciting Future,” Knowledge Millenium Summit (ASSOCHAM), New Delhi, India, March 28, 2006

Invited Chair and Opening Speaker for The Roundtable Session on  Science and Spirituality: Building the Bridge, ASSOCHAM Nano Bio  Summit, New Delhi, India, March 27, 2006

Invited Speaker: DARPA­-DSO, Meeting on Biosensors, Washington, DC, Feb­ruary, 2006

Chief Guest of Honor & Inaugural Keynote Speaker, "Elucidating the Biophysics of Yoga", 16th International Conference on Frontiers in Yoga Research and its Applications - "Yoga Works...but How?, Kolkatta, India, December 25-27, 2006

Invited Guest of the Hon. Chief Minister of Himachal Pradesh,  Presentation on Nanobiosym’s Vision for Improving Health Care in India, Himachal Pradesh, India, December 15-17, 2006


2005
Invited Speaker: “Some Emerging Prospects in Astrobiology”- Harvard­ Smithsonian Center for Astrophysics, Cambridge, MA, November, 11, 2005. Invited by Prof. Dimitar Sasselov.

Invited Speaker:  “Advancing Beneficial Nanotechnology: Focusing on the Cutting Edge.” 13th Foresight Conference on Advanced Nanotechnology, San Francisco, CA, October 26, 2005.

Invited Panel Speaker: Bob Metcalfe and the TR35 Panel, Technology Review’s Emerging Technologies Conference at MIT, Boston, MA, September 28, 2005.

Judge, MIT Technology Review Competition on SENS (Strategies for Engineered Negligible Senescence), based on an anti-aging prescription by Aubrey de Grey, Cambridge, MA, July, 2005.

MGH Grand Rounds Presentation, Clinical Pathology Conference, Boston, MA, April, 2004 (published in New England Journal of Medicine, May 12, 2005).

Invited Keynote Speaker: Osher Institute Dinner, Launching the Asian Medicine Program of Harvard Medical School, Cambridge, MA, February 16, 2005. Invited by Prof.Ted Kapatchuk.

Invited Seminar Speaker: “Emerging Prospects in Biocomputing,” Hughes Research Lab, Malibu, CA, February 11, 2005. Invited by Dr. Peter Petre and Dr. Matt Ganz.
2004
Invited Keynote Speaker:The Cosmology and Cosmogony of Life: Contemporary Issues,” Origin of Life Conference, Rome, Italy, November 10­-15, 2004. Invited by Dr. T.D. Singh.

Invited Keynote Speaker: “Breakthrough Nanoscale Technologies to Detect Trace Amounts of Biowarfare Agents,” Innovative Nanotechnologies II, Atlantic Nano­-Forum, Alexandria,VA, October 28, 2004.

Invited Speaker: Extraordinary Innovators Review, World Technology Summit, San Francisco, CA, October 7, 2004.

Invited Colloquium Speaker: Department of Physics Colloquium, Brandeis University, Waltham, MA, February 24, 2004. Invited by Prof. Seth Fraden.
Invited Colloquium Speaker: Department of Bioengineering, UCLA, Los Angeles, CA, January 22, 2004. Invited by Prof.Carlo Montemagno.
   2003
Invited Speaker: Seminar Series on Quantum Optics and Molecular Applications, Princeton University, Princeton, NJ, December 4, 2003. Invited by Prof. Marlan Scully.

Invited Keynote Speaker: International Symposium on Elucidating Biomolecular Networks by Single-­Molecule Technologies,  Monte-Verita, Ascona, Switzerland, October 27, 2003.

Invited Guest Speaker: DARPA/DSO International Workshop Building Blocks for   Engineering Devices and Systems, San Francisco, CA, August 20, 2003.

Invited Seminar Speaker: Physics of Complex Systems, Division of Physics and Astronomy, Free University of Amsterdam, Amsterdam, The Netherlands, June 30, 2003. 

Invited Speaker: Institute for Microsystem Technology & the Nano-­Physics Group, University of Freiburg, Germany, June 27, 2003.
Invited Colloquium Speaker: Department of Physics Colloquium, Zurich ETH, Zurich, Switzerland, June 25, 2003. Invited by Prof. Henry Baltes.

Invited Seminar Speaker: Physical Electronics Laboratory, Zurich ETH, Zurich, Switzerland, June 24, 2003. Hosted by Prof. Henry Baltes.

Invited Speaker: SPIE Conference on Fluctuations and Noise in Biological Systems, Santa Fe, NM, June 2, 2003.   Invited by Dr. Derek Abbott, conference co­-chair

2002
Invited Seminar Speaker: “Tuning and Switching the DNA Polymerase Motor with Mechanical Tension,” Center for Genomics Research, Harvard University, Cambridge, MA, October, 2002. Invited by Dr.Laura Garwin.

Chair, Emergence, Life, and Related Topics, Science and Ultimate Reality Symposium, Plainsboro, NJ, May, 2002.

Invited Speaker: “The Physics of Life,” Young Researchers’ Competition (Finalist), Science and Ultimate Reality Symposium, Plainsboro, NJ, May, 2002. See also Physics Today, May 2002. (In honor of John Wheeler’s 90th birthday)

    2001
Invited Speaker: Nanotechnology Workshop, Annual TIE Conference, Boston, MA, November 2001.

Invited Keynote Speaker, “Emerging Prospects in Nanobiotechnology,” TIE-­Atlantic, Boston, MA, October, 2001. Invited by Dr. Dinesh Patel, MGH.

Physics Colloquium Address,  Complex Systems Center, Northeastern Physics Department, Boston, MA, October 23, 2001.

Invited Speaker: “Environmentally Tuning Molecular Motors,” SFI Fellows-­at­-Large Gather­ing, Santa Fe Institute, Santa Fe, NM, August 10, 2001.

Invited Speaker: Future Technology Panel, World Technology Summit, London, UK, July 1­-2, 2001. Chaired by Dr. Phil Campbell, Editor-­in-­chief of Nature.

Invited Keynote Speaker: “How to Modulate the Speed and Direction of Molecular Engines that Replicate DNA,” IBC First  Meeting on Nanobiotechnology, San Diego, CA. July 16­-17, 2001

Invited Speaker: “The Information Content of Single Molecule Experiments,” 12th Annual Conversation, sponsored   by Journal of Biomolecular Structure and Dynamics, Albany, NY, June 2001.

Invited Speaker:  “Unifying Themes in Enzymatic Polymerization of DNA,” joint keynote with Prof. Tom Ellenberger, 12th Annual Conversation, sponsored by Journal of Biomolecular Structure and Dynamics, Albany, NY, June 2001.

Invited Seminar Speaker: “Tuning DNA Strings”, Departments of Chemistry and Physics at Harvard University, Cambridge, MA, June 2001.

 1992-99
Distinguished Student Research Award Acceptance Speech and Presentation, Seventh Annual Foresight Conference on Molecular Nanotechnology, Santa Clara, CA, October 11, 1999.

Invited Keynote Speaker:  “Some Future Prospects for Interfacing Physics and Bio-­Nanotechnology,” Nanotechnology Gathering on Openness in the Realms of “Stuand Bits, San Jose, CA, 1999.

Invited Speaker:  “Emerging Interdisciplinary Frontiers and Prospects for Establishing a Biological Physics Network in the Greater Boston Area,” Brandeis University’s Complex Fluids Workshop, Boston, MA, October, 1997. Invited by Prof. Alexander Grosberg, Panel Chair.

Invited Speaker:  “The Vision of HST-­Breaking Barriers between Disciplines to Catalyze the Scientific Discoveries of Tomorrow,” HST Visiting Commit­tee, Cambridge, MA, Fall 1997.

Chair, Think Tank meeting, Physics of DNA, Rowland Institute for Science, Cambridge, MA, July, 1997.

Opening Keynote Address, “The Vision of SETU,” SETU Conference, Stan­ford University, Palo Alto, CA, summer, 1994

Founding chair, SETU (Setu is Sanskrit for “bridge”), a humanitarian and visionary organization dedicated to building new high-tech, economic, and socio-political bridges between the U.S. and India.

Founding chair, SETU (Setu is Sanskrit for “bridge”), a humanitarian and visionary organization dedicated to building new high-tech, economic, and socio-political bridges between the U.S. and India.

Invited Speaker: “We Americans Should All Work Together to Fight Our Common Enemy of Racism,” Rodney King Rally, Stanford University, Palo Alto, CA, Spring 1992.

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Selected Press & Honors

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-  Lemelson-MIT Program, Inventor Archive, July, 2008.
 
-  Harvard-MIT HST Connector, Alumna Profile: “Building Bridges: Anita Goel brings together
   physics and medicine with nanotechnology,” Summer 2008.
 
-  “Nanobiosym CEO Dr. Anita Goel to Testify in US Senate,Forbes Online, April 21, 2008.
 
-  “Innovating in America Today,” Radio Interview, Host Tom Ashbrook, WBUR / NPR Boston.
   Aired September 27, 2007
 
-  Global Indus Technovator Award, Recognized at one of ‘Top Ten Global Technology Innovators in
   Science and Technology’ by MIT, December 4, 2006.
 
-  “Scientists do have Eureka moments,” India Abroad, November 9, 2006.
 
-  “Top 100 of the Nation’s Brightest Young Engineers,” National Academy of Engineering 12 th
   Annual Symposium on the Frontiers of Engineering, Dearborn, MI, July 2006.
 
-  “Molecularly Driven,” MIT Technology Review, January, 2006.
 
-  ‘TR35: World Top 35 Science & Technology Innovators Under 35,’ MIT’s Technology Revew
   Magazine, October, 2005.

-  “Using physics to understand biology,” Harvard Gazette, December 8, 2005.
    
-  “Top NRI Achievers,” HindustanTimes.com, October 2005.
    
-  “People in Physics” Profile, Physics Central Division, American Physical Society, 2003.

-  Kenneth Klivingston Fellowship in Bio-Dynamics, 2002-2003
 
-  Physics Today  - "15 Young Physicists on the Frontiers of Physics" in Honor of John
   Archibald Wheeler, Princeton, New Jersey, 2002.
 
-  NIH Medical Scientist Training Program (MSTP)
 
-  Interview published in The Committee of Sleep: How Artists, Scientists, and Athletes Use
   Dreams for Creative Problem Solving and How You Can Too
, D. Barrett, Crown Publishers,
   New York, 2001.

-  Martinos Scholar, Harvard-MIT HST Fellowship, 2000

-  Distinguished Student Award in Nanotechnology, presented at the 7th Annual Foresight
   Conference on Molecular Nanotechnology, Santa Clara, CA, 1999